3-O-Ethyl-L-ascorbic acid

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3-O-Ethyl-l-ascorbic acid

In the crystal structure of the title compound, C(8)H(12)O(6), mol-ecules are linked to each other by O-H⋯O hydrogen bonding.

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Allergic contact dermatitis caused by 3-o-ethyl-L-ascorbic acid (vitamin C ethyl).

Skin-lightening agents such as kojic acid, arbutin, ellagic acid, lucinol and 5,5′-dipropylbiphenyl-2,2′-diol are used in ‘anti-ageing’ cosmetics. Cases of allergic contact dermatitis caused by these skin-lightening agents have been reported (1, 2). Vitamin C and its derivatives have also been used in cosmetics as skin-lightening agents for a long time. Vitamin C in topical agents is poorly abs...

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2-O-Acyl-3-O-(1-acyloxyalkyl) Prodrugs of 5,6-Isopropylidene-l-Ascorbic Acid and l-Ascorbic Acid: Antioxidant Activity and Ability to Permeate Silicone Membranes

2-O-Acyl-3-O-(1-acyloxyalkyl) prodrug derivatives, 15, of 5,6-isopropylidene-l-ascorbic acid, VCA, and l-ascorbic acid, VC, have been characterized by measuring (1) their solubilities in water (SAQ) and in 1-octanol (SOCT); (2) the ability of one member of the homologous series, 15a, to diffuse through a silicone membrane from its application in propylene glycol:water (PG:AQ), 30:70; (3) the ab...

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L-Ascorbic Acid Peroxidase

Euglena gracilis was found to contain a peroxidase that specifically requires L-ascorbic acid as the natural electron donor in the cytosol. The presence of an oxidation-reduction system metabolizing L-ascorbic acid was demonstrated in Euglena cells. Oxidation of L-ascorbic acid by the peroxidase, and the absence of ascorbic acid oxidase activity, suggests that the system functions to remove H20...

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Potential Antitumor Activity of 2-O-α-d-Glucopyranosyl-6-O-(2-Pentylheptanoyl)-l-Ascorbic Acid

Intravenous administration of high-dose ascorbic acid (AA) has been reported as a treatment for cancer patients. However, cancer patients with renal failure cannot receive this therapy because high-dose AA infusion can have side effects. To solve this problem, we evaluated the antitumor activity of a lipophilic stable AA derivative, 2-O-α-d-glucopyranosyl-6-O-(2-pentylheptanoyl)-l-ascorbic acid...

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ژورنال

عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online

سال: 2008

ISSN: 1600-5368

DOI: 10.1107/s1600536808009963